Common equine eye emergencies

Veterinarian Anna O’Brien explains the causes and treatment of two common equine eye emergencies: corneal ulcers and eyelid lacerations. Items commonly found in the barn are often the culprit behind these traumatic injuries, Dr. O’Brien writes, but timely and appropriate veterinary care is usually enough to treat them effectively.

Unlike cattle, sheep, and goats, where the majority of eye issues are infectious, the majority of equine eye problems I see are trauma-related and result in corneal ulcerations.
It is my scientific opinion that horse eyes seem predisposed to getting poked out. This is most likely due to their anatomical location, which is namely right on the corners of the head, sticking out like headlights on an old VW Bug. Sharp objects apparently roam the Earth searching for horse eyes.

 

One of the most common culprits is, unfairly, the very food they eat. Long wiry pieces of hay shooting out of the trough or hay net are almost always in the “Usual Suspect” lineup when we play the game, “Who Poked Out My Horse’s Eye?”
As with cattle and small ruminants with inflamed and infected eyes, horses with corneal ulcerations exhibit similar signs. Horse owners will observe a forcefully closed eye, excessive tearing, with perhaps some head shyness or avoidance of light, depending on the disposition of the horse. As hours pass, the cornea may become cloudy, and white or yellowish discharge instead of tears may weep from the eye.
The beginning of any emergency equine exam starts with sedation and a nerve block of the upper eyelid to allow me to open the eye wide. Then, if I suspect trauma and corneal damage, I’ll apply a special stain to the eye. This stain will glow neon green if the delicate tissue underneath the outer layer of the cornea is exposed due to ulceration. Sometimes the area of ulceration is literally the size of a needlepoint. But no matter what the size, ulceration is ulceration and requires treatment.
Most mild corneal ulcerations can be treated with topical antibiotic ointment and some pain medication. Others are more complicated. If the ulcer is large, healthy epithelial tissue sometimes has difficulty adhering to the cornea, and healing is non-productive. If this is the case, we sometimes have to scrape the eye to remove the old tissue, giving the new tissue something to adhere to.
Other times, the ulceration has allowed bacteria inside the eye, setting up what is called a stromal abscess. These can be very difficult to treat, requiring intensely frequent applications of multiple types of medications. At the very worst, an ulcer can be deep enough to rupture the eye. This is why eye issues are always an emergency, since you can never be sure at first exactly how deep the problem really is.
Eyelid lacerations are another extremely common equine eye problem. Like the ubiquitous hay stalk waiting to cause a corneal ulcer, another common barn object is frequently the cause of dangling eyelids: the hooks at the ends of water bucket handles. These curved metal pieces on the sides of hanging buckets just seem to jump out at horse eyes and grab on to upper eyelids for dear life, resulting in a gruesome find for the owner the next morning.
Luckily, eyelid lacerations usually look much worse than they really are. They bleed a lot and swell a lot, making the horse look like he’s been in a bar fight involving brass knuckles and a switchblade. However, after sedation and nerve blocks and a little careful stitching with very fine suture material and a teeny tiny needle, the horse usually comes out of it looking much better. The only challenge is not letting the horse rub his head once the stitches become itchy a few days later.
Sometimes with an eyelid laceration, the owner will ask why I don’t just trim off the lacerated portion rather than sew it back on. The answer is that horse’s eyes are so big, they need all the lid they can get. Eyelids are the best protection the eyeball has against the pokey world and even a small missing portion can sometimes result in chronic eye irritation.
Although we’ve covered the traumatic cases of equine eye emergencies, we haven’t even touched on things like cancer of the eye and a weird thing only horses get called “moon blindness.” Shall we say, stay tuned?

Pets in pain deserve the best care

While there are lifestyle changes that can help alleviate arthritic pain in pets, such as soft beds, glucosamine supplements, proper exercise and weight management, veterinarian Marty Becker suggests owners get educated about the medications available to help treat chronic pain in pets. Veterinarians can provide medications that are safe and effective and tailored for each pet’s needs. The Sacramento Bee (Calif.) (free registration)

There are things you can do to treat your dog’s arthritis without using a prescription pain medication from your veterinarian, such as providing soft beds (warmed in the winter), glucosamine supplements and regular moderate exercise, and getting your pet down to a proper weight. But if these measures are not enough, you need to discuss effective prescription pain control with your veterinarian.

I know a little something about chronic pain, thanks to a chronic neurological condition, and I can tell you it’s a miserable way to spend a life. And yet so many pets are in such misery because their owners have “heard” that nonsteroidal anti-inflammatory drugs (NSAIDs) are deadly.

While no medication, however helpful, is without the potential for side effects (including very serious ones), the NSAIDs available from your veterinarian have high marks for safety as long as precautionary protocols are followed, including diagnostic tests to spot possible problems with internal organs.

Discuss all your options and all the precautions, and work with your veterinarian to ease your pet’s suffering while minimizing the potential for side effects. The U.S. Food and Drug Administration has an excellent free publication on NSAIDs (tinyurl.com/petpainmeds), and I encourage you to download it.

– Dr. Marty Becker

Read more here: https://www.sacbee.com/2013/02/19/5194441/work-with-a-vet-to-ease-dogs-discomfort.html#storylink=cpy

Tailored care ensures dental cleanings are as safe as possible

February is National Pet Dental Health Month, but pets’ oral health should be a year-round priority because dental disease can lead to systemic problems involving the liver, kidneys and heart, writes veterinarian Karen Dye. Fear of anesthesia is not a reason to forgo veterinary dental cleanings, Dr. Dye notes, because thorough lab tests before the procedure, appropriate anesthetic choices and monitoring during anesthesia all tailored to a specific breed and animal help ensure a pet’s safety. The Culpeper Star-Exponent (Va.)

Q:  I know February is National Pet Dental Health Month, but I am worried about the risk of anesthesia.

A:  Anesthesia always involves some risk, but there are many precautions that can make anesthesia as safe as possible.  The risks of dental disease usually outweigh the risks of anesthesia.  Bacteria from dental disease can affect the whole body including the heart, liver and kidneys.

Prior to any patient being anesthetized, a complete physical exam should be performed to ensure the safest anesthetic experience.  Pre-anesthetic blood tests should also be completed in order to detect anemia or problems with liver health, kidney function, blood sugar, or serum proteins that would otherwise go unnoticed.  Having the complete picture of your pet’s health, veterinarians can individually tailor the choice of anesthetic drugs, keeping your pet as safe as possible.

At my practice, we use only uses the safest, most modern anesthetic medications for any procedure.  Most of these drugs are used every day in human hospitals.  Your pet will benefit from the advanced safety of modern anesthesia.  State of the art computerized monitoring equipment is also used to keep every patient as safe as possible.  Your pet’s heart rate, EKG, respiration, blood oxygen saturation, and core body temperature will be constantly monitored during the procedure using the latest VetSpecs PC-VSM3 multi-parameter digital anesthetic monitor.

Tracheal intubation during general anesthesia maintains adequate ventilation.  The simple act of placing a tracheal tube will ensure your pet receives enough oxygen throughout the procedure, a key component in anesthesia safety.

Intravenous fluid therapy will help protect your pet’s kidneys from damage during anesthesia.  Healthy kidneys are vital to a long, happy life.  No human hospital would ever perform general anesthesia without IV fluids, yet many veterinary hospitals skip this important step.  The IV catheter placed to administer fluids can also be life-saving.  If minor abnormalities occur during the procedure, appropriate medications can be rapidly administered intravenously when a catheter is present.  With early detection from a computerized monitor, and speedy treatment through a catheter, our medical team can often keep small problems from turning into larger ones.

To protect against dangerously low body temperature, we use a high tech water circulating heating pad system.  This system will not burn the patient.  When we say as safe as possible, we mean it.

From the moment your pet is anesthetized until after he or she wakes up, a highly educated member of our medical team is by his or her side.  No anesthetized patient is ever left alone, not even for a second.  Our professional staff regularly attends continuing education courses on the newest, safest anesthetic techniques.  We will be there to hold your pet’s paw.

We use breed-specific profiling as well.  Certain breeds carry specific predispositions that should be addressed prior to anesthesia.  Examples include clotting disorders in Dobermans, heart murmurs in Maine Coon cats, and drug sensitivities in Greyhounds.  Brachycephalic breeds (bulldogs, pugs, Boston terriers, Pekingese) can have brachycephalic syndrome with increased respiratory effort with the potential for upper airway obstruction.  We avoid excessive sedation with brachycephalic breeds, administering pre-medications at half-dose.  We also pre-oxygenate brachycephalic breeds and use short-acting induction agents.  Appropriate sized tracheal tubes are selected and extubation does not occur until your pet is sitting up, vigorous, bright and alert.  Sighthounds (greyhounds, whippets, Borzoi, Salukis) have delayed metabolism, lower body fat percentage and are at risk for hypothermia.  These risks are kept very low since we use high tech monitoring equipment and warm water circulating heating pads.  Herding breeds (collies, shelties, Australian shepherds and border collies) can have a mutation resulting in accumulation of certain drugs in the cerebral spinal fluid, followed by excessive sedation and respiratory depression.  For these patients, we reduce certain medications by 25% and monitor carefully.

In conclusion, it is important to keep your pet healthy and dental health is a critical component of overall health and well being.  Modern protocols, like the ones at Clevengers Corner Veterinary Care, minimize anesthetic risk and maximize the benefit of a clean, healthy mouth.

Dr. Dye practices companion animal medicine and surgery at Clevengers Corner Veterinary Care.  She and Dr. Watts can be reached at (540)428-1000 or through ClevengersCorner.com.

Study assesses neutering and health conditions in dogs

Neutering dogs may impact the occurrence of disorders including hip dysplasia, cranial cruciate ligament tears, lymphosarcoma, mast cell tumors and hemangiosarcomas, according to a study led by veterinarian Benjamin Hart at the University of California, Davis, School of Veterinary Medicine. Researchers evaluated the medical records of 759 golden retrievers, male and female, finding that early and late sterilization were associated with an increased occurrence of certain disorders. However, Dr. Hart noted that disease vulnerability may vary among breeds, and any connection between neutering and health conditions is likely multifaceted. PhysOrg.com

The study, which examined the health records of 759 golden retrievers, found a surprising doubling of hip dysplasia among male dogs neutered before one year of age. This and other results will be published today (Feb. 13) in the online scientific journal PLOS ONE. “The study results indicate that dog owners and service-dog trainers should carefully consider when to have their male or female dogs neutered,” said lead investigator Benjamin Hart, a distinguished professor emeritus in the UC Davis School of Veterinary Medicine. “It is important to remember, however, that because different dog breeds have different vulnerabilities to various diseases, the effects of early and late neutering also may vary from breed to breed,” he said. While results of the new study are revealing, Hart said the relationship between neutering and disease-risk remains a complex issue. For example, the increased incidence of joint diseases among early-neutered dogs is likely a combination of the effect of neutering on the young dog’s growth plates as well as the increase in weight on the joints that is commonly seen in neutered dogs. Dog owners in the United States are overwhelmingly choosing to neuter their dogs, in large part to prevent pet overpopulation or avoid unwanted behaviors. In the U.S., surgical neutering—known as spaying in females—is usually done when the dog is less than one year old. In Europe, however, neutering is generally avoided by owners and trainers and not promoted by animal health authorities, Hart said. During the past decade, some studies have indicated that neutering can have several adverse health effects for certain dog breeds. Those studies examined individual diseases using data drawn from one breed or pooled from several breeds. Against that backdrop, Hart and colleagues launched their study, using a single hospital database. The study was designed to examine the effects of neutering on the risks of several diseases in the same breed, distinguishing between males and females and between early or late neutering and non-neutering.                                        google_protectAndRun(“render_ads.js::google_render_ad”, google_handleError, google_render_ad);     The researchers chose to focus on the golden retriever because it is one of the most popular breeds in the U.S. and Europe and is vulnerable to various cancers and joint disorders. The breed also is favored for work as a service dog. The research team reviewed the records of female and male golden retrievers, ranging in age from 1 to 8 years, that had been examined at UC Davis’ William R. Pritchard Veterinary Medical Teaching Hospital for two joint disorders and three cancers: hip dysplasia, cranial cruciate ligament tear, lymphosarcoma, hemangiosarcoma and mast cell tumor. The dogs were classified as intact (not neutered), neutered early (before 12 months age), or neutered late (at or after 12 months age). Joint disorders and cancers are of particular interest because neutering removes the male dog’s testes and the female’s ovaries, interrupting production of certain hormones that play key roles in important body processes such as closure of bone growth plates, and regulation of the estrous cycle in female dogs. The study revealed that, for all five diseases analyzed, the disease rates were significantly higher in both males and females that were neutered either early or late compared with intact (non-neutered) dogs. Specifically, early neutering was associated with an increase in the occurrence of hip dysplasia, cranial cruciate ligament tear and lymphosarcoma in males and of cranial cruciate ligament tear in females. Late neutering was associated with the subsequent occurrence of mast cell tumors and hemangiosarcoma in females. In most areas, the findings of this study were consistent with earlier studies, suggesting similar increases in disease risks. The new study, however, was the first to specifically report an increased risk of late neutering for mast cell tumors and hemangiosarcoma. Furthermore, the new study showed a surprising 100 percent increase, or doubling, of the incidence of hip dysplasia among early-neutered males. Earlier studies had reported a 17 percent increase among all neutered dogs compared to all non-neutered dogs, indicating the importance of the new study in making gender and age-of-neutering comparisons. More information: dx.plos.org/10.1371/journal.pone.0055937Journal reference: PLoS ONE Provided by UC Davis
Read more at: https://phys.org/news/2013-02-golden-neutering-affects-dog-health.html#jCp

Canine intestinal disorders explained

Veterinarian Karen Dye explains two canine intestinal disorders: hemorrhagic gastroenteritis and inflammatory bowel disease. The symptoms of intestinal disease are nonspecific, but characteristics such as breed, as well as blood tests of metrics such as packed cell volume, help the veterinarian pinpoint the cause, Dr. Dye writes. The recommended treatment varies depending on the diagnosis but usually includes fluids, medications and dietary changes. The Culpeper Star-Exponent (Va.)

Ask Dr. Dye – Dr. Karen Dye The Daily Progress

Q: What is HGE?

Hemorrhagic Gastroenteritis (or HGE) is a serious and potentially fatal disease of the intestinal tract.  The cause is unknown, and this condition occurs most commonly in smaller breed dogs, although it can arise in any breed. The onset of bloody diarrhea is quick and dehydration occurs rapidly. Vomiting also commonly occurs. If not treated promptly, the dog may go into shock.

No specific tests are available to diagnose HGE, however, a packed cell volume (PCV) being elevated along with clinical signs and physical exam lead to a diagnosis. A normal PCV for a healthy dog would be 37-55%, meaning 37-55% of the blood volume should be red blood cells (the rest being fluid and white blood cells). When a patient becomes very dehydrated, there is less fluid in the blood stream, and the result is a rising percentage of red blood cells.  A dog with HGE will have a PCV greater than 60%. Measurement of total protein is often done with a PCV.

Dogs with HGE will have a lower than normal total protein.

During an episode of hemorrhagic gastroenteritis, the intestinal lining and intestinal blood vessels become permeable to fluid. Fluid and associated proteins leak out of the blood vessels and into the intestine.  The blood cells are too large and stay behind.  It is in this way that fluid is lost into the intestine, causing diarrhea and dehydration.  The PCV rises and the total protein decreases.

Treatment involves hospitalization and appropriate intravenous fluid therapy.  Symptoms such as vomiting and nausea can be controlled with medications by injection since the patient should not receive anything by mouth for at least one day.  A bland diet can be added slowly while continuing fluid support.  Aggressive fluid therapy will decrease the PCV into a normal range and prevent the patient from going into shock.  Often antibiotics are indicated as well.  It is usual for the patient to be hospitalized for several days receiving IV fluid support.

It is not contagious or genetic, and we still need further research into the cause as it remains unknown.  Sometimes, stress or hyperactivity precedes the onset of disease.

Q: What is IBD?Inflammatory Bowel Disease (IBD) is a complex set of diseases all grouped together as IBD.  There are different types of inflammatory bowel disease and the only way to definitively diagnose it is via intestinal biopsy and histopathology. Therefore, IBD is a disease that can be difficult to diagnose since many other causes of diarrhea present similarly to IBD.  Inflammatory bowel diseases are the most common cause of long-term vomiting and diarrhea in dogs and cats.  The cause of IBD is not completely understood.  The gastrointestinal tract becomes invaded by inflammatory cells, including lymphocytes, plasma cells, eosinophils, macrophages, and/or neutrophils.  These infiltrates cause damage to the mucosal lining of the intestines, causing diarrhea and/or vomiting.  It is believed that with IBD, the immune system reacts abnormally to normal bacteria in the intestines.

Diagnosis is based on clinical signs (chronic diarrhea, vomiting, and weight loss) in addition to the exclusion of other diseases causing similar symptoms. Other diseases include metabolic disease, infectious disease, obstructive disorders and neoplasia.  To confirm the diagnosis of IBD, biopsies must show histological evidence of cellular infiltrates and changes to the intestinal architecture.

Dietary treatment is of utmost importance. Up to 60% of dogs and cats with IBD will benefit from a special diet prescribed by your veterinarian. Sometimes antimicrobial therapy is necessary as well as a novel diet.  Immunosuppressive drugs such as prednisone or cyclosporine are reserved for cases that fail to respond to nutritional and antimicrobial therapy.

There is no cure for inflammatory bowel disease.  It is a disease that is controlled and relapses are possible.  Dietary compliance is important.

Dr. Dye practices at Clevengers Corner Veterinary Care and can be reached at 540-428-1000 or through ClevengersCorner.com.

Cat’s weight-loss program includes swimming

Holly, an 18-pound cat, is swimming off her extra pounds since she won’t engage in any other form of exercise, according to her owner. Swimming therapy is used routinely in dogs for weight loss or to aid rehabilitation after surgery, but it’s less common to see a cat in the pool. According to the Association for Pet Obesity Prevention, 55% of cats and 53% of dogs are too heavy, putting them at greater risk of serious illnesses including diabetes, arthritis and some cancers. WJLA-TV (Washington, D.C.) (1/31), TODAY/Animal Tracks blog (1/31)

It’s not every day that you see a swimming cat.

Holly in the pool.

But in Loudoun County, a particularly rotund 13-year-old cat  regularly glides into the pool to swim laps. It’s part of her weight loss  plan.

Athough it’s odd to see a cat swimming, it’s the only exercise she’ll agree  to.

“She won’t do anything else,” says Dani Lawhorne of her cat, Holly. “I’ve  tried to take her outside. She doesn’t like the outdoors so she won’t run  around, she won’t play with cat toys, she doesn’t like cat nip. Anything normal  that cats like, she just doesn’t like.”

And so once a week, Holly suits up at the Olde Towne Pet Resort.

Weighing in at almost 20 pounds, Holly’s weight loss goal is approximately  six to seven pounds.

According to the Association for Pet Obesity Prevention, 53 percent of dogs  and 55 percent of cats are overweight or obese. That’s more than 88 million  pets.

And the effects can be life-threatening, increasing the risk of arthritis,  diabetes and even cancer.

“I don’t think people appreciate the seriousness of long-term overweight body  condition,” says Dr. Robert Justin, an internal medicine veterinarian.

If your pet is overweight, talk with your veterinarian about starting an  exercise program and choosing a lower fat food. Slimming down is especially  important for overweight pets who are injured.

Thanks to her new workout regimen and a healthier diet, Holly’s making some  progress. She’s lost about a pound the past six months.

Read more: https://www.wjla.com/articles/2013/01/loudoun-county-cat-swims-laps-to-lose-weight-84707.html#ixzz2KAPxbjHm

Good news for Iraq war vet’s service dog: Biopsy shows tumor is benign

SANTA CRUZ — An Iraq War veteran has received a slew of good fortune during the past few days — learning late Monday morning that the tumor removed from her four-legged, steadfast companion last week is benign.

Devon, a 7-year-old golden retriever, underwent surgery early Friday morning to have the mass removed from his left front paw. It was shipped to a lab for further testing, and if the results showed a malignancy, chemotherapy or radiation treatments likely would have been needed.

Dr. David Shuman, who operates the Santa Cruz Westside Animal Hospital, donated his services to remove the growth, and when the lab learned of Santa Cruz resident Tori Stitt’s story, “they donated their services and put ‘STAT’ all over it,” he said Monday.

Meanwhile, when the community learned the invaluable services Devon provides to help Stitt cope with post-traumatic stress disorder — including licking her awake to interrupt persistent nightmares — they eagerly opened their wallets, donating about $8,000.

Shuman and Stitt both expressed their appreciation for the outpouring of support.

“It’s amazing to see how the community will come together to support someone like me,” Stitt said. “The cards, the checks — it’s like, wow.”

Devon entered Stitt’s life in 2009, not long after the former Navy lieutenant returned from a yearlong deployment to northern Iraq. During her time there, she trained staff members how to defuse improvised explosive devices and witnessed many of her trainees injured and killed while working in the field.

Plagued by recurring nightmares, and increasingly isolating herself from society, she sought help from the Assistance Service Dog Educational Center, a nonprofit that provides service dogs to disabled veterans.

Ever since, Stitt has become more outgoing and involved in the community, befriending such staunch supporters as Santa Cruz resident Rachel Boyd, who cares for Devon while his owner works. He was back in Shuman’s care Monday, getting his sutures removed and paw rebandaged.

“As soon as the skin heals and we make sure everything’s covered over, it’s a done deal,” Shuman said.

Meanwhile, the funds donated over the weekend have been set aside in a client account.

“He should be a very well cared for dog for the rest of his life,” Shuman said.

By Kimberly White

Santa Cruz Sentinel

Posted:   02/04/2013 01:51:09 PM PST

February is National Pet Dental Health Month

Poor oral health has serious repercussions, AVMA reminds owners
The AVMA designated February as National Pet Dental Health Month to highlight the importance of oral care for overall animal health. The majority of adult cats and dogs have dental disease, and if left untreated, the condition can have serious consequences. “Dental problems are extremely common, and many are very painful and can lead to serious systemic conditions,” said AVMA President Dr. Douglas Aspros. “An untreated dental infection can spread to the heart, kidneys and other organs and suddenly become life-threatening.”
PetSide.com

Sponsored by the American Veterinary Medical Association, (AVMA) the month of February has been set aside as National Pet Dental Health Month. And while I’ll wager almost anything that the majority of humans don’t consider a trip to the dentist to be one of their top 10 most favorite things to do, it’s no secret that regular dental checkups are essential to maintain overall good health. It’s equally just as important for pet parents to provide regular dental care for their pets.

According to studies made by the American Animal Hospital Association, (AHHA) sadly, 85 percent of dogs and cats over the age of 3 years have already suffered dental or gum disease. Without regular dental care and cleaning, pets can develop gingivitis, (an often painful inflammation of the gums) from the bacterial laden plaque which, if not taken care of on a regular basis, develops into tarter or calculus.

The AAHA studies also found that two-thirds of pet guardians do not provide the regular dental care recommended by veterinarians.  Kate Knutson, co-owner of the Pet Crossing Animal Hospital and Dental Clinic, located in Bloomington, Minnesota, said, “We believe that one of the most important parts of pets’ health care is attention to dental disease.”

Board president of the Academy of Veterinary Dentistry and certified veterinary dentist, Dr. Brook A. Niemiec said, “Unfortunately, only about one percent of pet owners brush their pet’s teeth. Not only do more pet owners need to brush their pet’s teeth, they should also use chew toys, treats and rawhides to help keep their pet’s teeth clean.”

Dr. Douglas Aspros, President of the AVMA said, “Dental problems are extremely common, and many are very painful and can lead to serious systemic conditions”. He reminds pet guardians that, “an untreated dental infection can spread to the heart, kidneys and other organs, and suddenly become life threatening.”

Although the AVMA is promoting Pet Dental Health Month in February, at the same time the organization is reminding dog and cat owners that in addition to making an appointment with their veterinarian for a complete dental checkup and cleaning, that learning how to brush their pet’s teeth and do so on a regular basis that their veterinarian recommends is equally essential.

Learn the symptoms of pet dental disease which many are hard to ignore. One of the first signs of gum disease is unrelenting bad breath. Additionally, pets may exhibit: difficulty in eating, pawing at their mouth, gums that are sore and red gums, and tooth discoloration caused by tarter.

In order to celebrate Pet Dental Health Month, many veterinary practices are offering a special discount for their pet’s oral care.

Cat’s bite wound should be treated by a veterinarian

Feline bites pose problems for cats and humans, writes veterinarian Marty Becker, because bacteria from a cat’s mouth can cause a serious infection. Cats bitten by another feline may need surgical and antibiotic treatment as well as drain placement by a veterinarian to completely clear the infection, Dr. Becker writes. Humans who are bitten by cats should thoroughly wash the area and be evaluated by a physician, he adds.

Q.  My cat got into a fight again and now he has an infection. I just can’t afford another trip to the vet. What can I do at home?

A.  You need to take your cat to the veterinarian, because cat bites can be very serious. After this issue is resolved, you can save money through prevention – and that means keeping your cat inside.

Why? Because this common feline health problem is often the result of a puncture wound, specifically a bite from another cat during a fight over territory or mates.

Nearly every free-roaming cat needs to see a veterinarian from time to time to have an abscess treated – and by “treated,” I mean surgically opened, flushed clean of debris, and sometimes temporarily held open by drains to let the wound heal with the help of time and some strong antibiotics.

A cat’s mouth is a nasty mix of bacteria, and once that bacteria gets punched into another cat’s body, the result will probably be an abscess. Think about it – bacteria being injected with two hypodermic needles (the cat’s fangs) into a perfect incubator (another cat’s 101-plus-degree body). The only possible outcome is infection.

That’s also why even relatively minor cat bites can become serious medical issues for humans, leading to hospitalization in some cases. Any time you’re bitten or scratched by an animal, you should wash the area immediately with soap and water, and have the wound checked out by your doctor.

– Dr. Marty Becker

Read more here: https://www.sacbee.com/2013/02/05/5165202/cats-infected-wound-needs-vet.html#storylink=cpy

Canine cancer patients might one day help humans

Veterinarians and other scientists have been studying canine cancer patients’ DNA to identify mutations involved in several types of cancer, many of which also affect humans, such as lymphoma and osteosarcoma. The findings will likely lead to better diagnostics and treatments for animals and humans alike. “The key to unlocking some of nature’s most perplexing puzzles in human health has actually stood right next to us, wagging its tail,” said Matthew Breen, a genomics professor at North Carolina State University’s College of Veterinary Medicine. Santa Cruz Sentinel (Calif.)

By Elizabeth Devitt

Jasper, a 7-year-old rescue dog from San Jose, has a personality that endears him to everyone — even to cats. He also has lymphoma, a cancer that sprouts from the body’s defense system and is similar to non-Hodgkin lymphoma in people.

Right now, Jasper’s treatment plan is based on laboratory tests, ultrasounds and the expertise of his veterinarian, Linda Fineman, a cancer specialist at the SAGE center in Campbell. Although he’s doing well after his first round of treatment, the hardest part is not knowing how long it will help him, said his owner, Catherine Jacobsen.

In the future, however, tests on Jasper’s DNA could determine the best medications for him and show how long they’ll work, according to scientists who study the DNA of dogs. And those researchers are increasingly discovering that cancer and other diseases are caused by the same genetic mutations in pooches and people.

So as scientists develop new therapies for canine cancers, they’re also finding more effective methods to treat similar problems in humans.

“The key to unlocking some of nature’s most perplexing puzzles in human health has actually stood right next to us, wagging its tail,” said Matthew Breen, a genomics professor at North Carolina State University College of Veterinary Medicine.

Scientists got a huge new asset when the first national canine tumor bank opened at the end of October, Breen said. Researchers now have a one-stop shopping source of samples from the bank, developed as part of the Canine Comparative Oncology and Genomics Consortium in Bethesda, Md.

 

Good models

Our four-legged friends are good models for studying human disease because they share our environment, so they’re exposed to the same factors that may lead us to develop cancer, said geneticist Heidi Parker of the National Human Genome Research Institute in Bethesda.

“They’re living life with us and getting old like the rest of us,” she said.

But the shorter lifespan of dogs means they get cancer faster, so scientists don’t have to wait decades to find out which treatments work better, said Michael Kent, co-director of the Comparative Cancer Center at the UC Davis School of Veterinary Medicine.

Centuries of close breeding in canines have made it easier to hunt for genetic links to disease. When breeders select for specific features in dogs — a curly coat or a stout body — they unwittingly choose other traits, Parker said. In time, certain maladies became linked with particular breeds: Dobermans frequently have blood clotting disorders, and dachshunds get day blindness.

Looking for faulty gene

Once scientists find the location of DNA that causes a disease in dogs, they also have a better idea of where to look for the faulty genes in people. With a common genetic basis for disease, researchers can use similar tools to fight cancer in canines and humans.

When Molly got a lump in her mouth, the biopsy for the 12-year-old beagle from Aptos determined it was a melanoma, the most common malignant cancer in a dog’s mouth. Fortunately, there’s now a vaccine to help fight this cancer, said Dr. Theresa Arteaga, Molly’s oncologist at Pacific Veterinary Specialists in Capitola.

Scientists knew that only melanoma cells make a protein called tyrosinase. So a team of researchers that included Arteaga tested a vaccine for dogs that tricked the immune system into attacking the cells with tyrosinase. The vaccine stopped tumor growth. In many cases, it also kept the cancer from spreading.

Same gene

People get melanomas, too. Unlike the cancer in dogs, tumors in humans tend to show up on the skin, but the cancer still uses the same gene for tyrosinase. So after the vaccine was successfully developed for dogs in 2007, those studies led to approval of similar vaccines for clinical trials in people.

Osteosarcoma is another disease in which canine research has already boosted treatment for people. This cancer is common in big breeds, such as great danes and Irish wolfhounds. It usually attacks the leg bones and then travels to the lungs. In people, it’s often a pediatric disease, afflicting fewer than 1,000 patients a year. It’s hard to study in children because so few get the disease, but more than 10,000 dogs are diagnosed with it annually.

Disease spreads

Even after surgery to remove the cancer, osteosarcoma still spreads to the lungs — in dogs and people. Researchers, however, discovered that this cancer changes the DNA of dogs in several ways. With that information, they found more effective cocktails of drugs and lowered the rate of the cancer spreading to the lungs. These findings led the U.S. Food and Drug Administration to fast-track approval for similar medications for people, leading to longer life expectancies, said veterinarian Cecile Siedlecki, a cancer specialist in San Leandro who also consults with physicians.

Dog vs. human

Although scientists have studied the similarity of health problems at both ends of the leash for decades, research exploded after the entire genome was sequenced for a boxer named Tasha in 2004 (about a year after the human genome was first sequenced), said Elaine Ostrander, chief of the cancer genetics branch at the National Institutes of Health in Bethesda. Results of the Dog Genome Project were stored at a group of institutions, including UC Santa Cruz, and made available to researchers around the world.

Gleaning links to disease from dog genes is like a long, long game of fetch. It’s played with short sequences of DNA. Each snippet of the genetic code is made with combinations of only four building blocks: A, T, G or C. The sequence of those combinations create orders that tell every cell exactly how to make everything the body needs.

If that sequence gets shuffled — mutated — then something gets built incorrectly. Sometimes, those errors cause disease.

Variation search

So scientists search for tiny variations in those building blocks of DNA, called SNPs (single nucleotide polymorphisms), which show up in dogs with specific traits. Any change at these key locations in the genome are compared with DNA samples from healthy dogs and samples from diseased dogs to find those SNPs linked with the disease. From then on, it’s a matter of finding the genes tagged to the SNPs, explained Breen, of the North Carolina State University College of Veterinary Medicine.

The more tumor samples from dogs that are available for scientists to study, the faster they’ll learn the genetic mechanisms that cause disease, Breen said.

Hundreds of owners have found the courage to get samples taken from their dogs and sent for studies, Breen said. “Their dog might make a difference for the next generation.”

And some of that next generation might walk on two legs instead of four.

To get involved

Registration just opened for the Canine Lifetime Health Project, managed by the Morris Animal Foundation in Denver. The long-term study follows dogs into their senior years. Researchers will gather information about everything from dogs’ daily eating and exercise routines to annual lab tests. Then scientists will sift through that data to link factors like health, genetics and environment to cancer and other diseases. The project is enrolling 3,000 pedigreed golden retrievers, younger than 2 years of age, but any dog owner can join the list for later studies, said project director Mike Guy. Even people without dogs can sign up for updates, he said. For information, go to www.caninelifetimehealth.org.